While Café Africa International is based in Switzerland, each Café Africa operates as an independent, registered organisation in:

• Uganda (Café Africa Uganda)
• Tanzania (Café Africa Tanzania)
• Democratic Republic of Congo (Café Africa RDC)

Café Africa has also worked in Cameroun.

Café Africa in each country is registered as a national non-profit organization in its host country. Each Café Africa is self-supporting, developing its own programme and raising its own funding, and each is governed by its own board.